Comparison 1. BMT vs PBSCT.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall survival	6	1330	Hazard Ratio (Fixed, 95% CI)	1.07 [0.91, 1.25]
1.1 Related donor	5	804	Hazard Ratio (Fixed, 95% CI)	1.12 [0.91, 1.39]
1.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	1.0 [0.79, 1.27]
2 Disease free survival	6	1225	Hazard Ratio (Fixed, 95% CI)	1.04 [0.89, 1.21]
2.1 Related donor	5	699	Hazard Ratio (Fixed, 95% CI)	1.07 [0.87, 1.30]
2.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	1.01 [0.80, 1.28]
3 Incidence of relapse	3	737	Hazard Ratio (Fixed, 95% CI)	1.30 [0.98, 1.72]
3.1 Related donor	2	211	Hazard Ratio (Fixed, 95% CI)	2.73 [1.47, 5.08]
3.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	1.07 [0.78, 1.47]
4 Transplant related mortality	3	758	Hazard Ratio (Fixed, 95% CI)	0.98 [0.76, 1.28]
4.1 Related donor	2	232	Hazard Ratio (Fixed, 95% CI)	1.04 [0.65, 1.66]
4.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	0.96 [0.70, 1.31]
5 Incidence of overall chronic GvHD	4	1121	Hazard Ratio (Fixed, 95% CI)	0.72 [0.61, 0.85]
5.1 Related donor	3	595	Hazard Ratio (Fixed, 95% CI)	0.74 [0.60, 0.92]
5.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	0.70 [0.54, 0.90]
6 Incidence of extensive chronic GvHD	4	765	Hazard Ratio (Fixed, 95% CI)	0.69 [0.54, 0.90]
7 Incidence of acute GvHD grade II‐IV	6	1330	Hazard Ratio (Fixed, 95% CI)	1.03 [0.89, 1.21]
7.1 Related donor	5	804	Hazard Ratio (Fixed, 95% CI)	1.08 [0.88, 1.33]
7.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	0.98 [0.77, 1.24]
8 Incidence of acute GvHD grade III‐IV	3	925	Hazard Ratio (Fixed, 95% CI)	0.75 [0.55, 1.02]
8.1 Related donor	2	399	Hazard Ratio (Fixed, 95% CI)	0.71 [0.44, 1.13]
8.2 Unrelated donor	1	526	Hazard Ratio (Fixed, 95% CI)	0.79 [0.52, 1.19]
9 Time to neutrophil engraftment	5	662	Hazard Ratio (Fixed, 95% CI)	1.96 [1.64, 2.35]
10 Time to platelet engraftment	4	333	Hazard Ratio (Fixed, 95% CI)	2.17 [1.69, 2.78]