Table 4.

Clinical outcomes at 30 days and one year^a.

	Outcomes at 30 days				Outcomes at 1 year
	Controls N = 428	Cases N = 132	Subdistribution hazard ratio (95% CI)	p-value	Controls N = 428	Cases N = 132	Subdistribution hazard ratio (95% CI)	p-value
Death	9 (2.2%) [0]	23 (19.2%) [0]	9.45 (4.37–20.44)	<0.001	29 (7.7%) [0]	26 (30.7%) [0]	4.30 (2.58–7.17)	<0.001
Cardiovascular death	3 (0.7%) [6]	5 (4.1%) [18]	5.76 (1.38–24.07)	0.02	9 (2.4%) [20]	5 (5.5%) [21]	2.28 (0.80–6.50)	0.12
Non-cardiovascular death	3 (0.7%) [6]	17 (14.3%) [6]	20.64 (6.05–70.40)	<0.001	13 (3.5%) [16]	19 (21.8%) [7]	6.62 (3.42–12.82)	<0.001
Unclear death	3 (0.7%) [6]	1 (0.8%) [22]	1.14 (0.12–10.87)	0.91	7 (1.9%) [22]	2 (2.5%) [24]	1.22 (0.26–5.79)	0.81
Myocardial infarction	3 (0.7%) [8]	3 (2.5%) [23]	3.44 (0.70–16.96)	0.13	7 (1.8%) [27]	3 (3.2%) [26]	1.73 (0.47–6.37)	0.41
Unplanned revascularisation	0 (0.0%) [9]	0 (0.0%) [23]			0 (0.0%) [29]	1 (1.7%) [26]
Cerebrovascular event	7 (1.7%) [9]	1 (0.8%) [23]	0.49 (0.06–3.99)	0.51	11 (2.9%) [26]	2 (2.2%) [26]	0.72 (0.16–3.31)	0.67
Stroke (ischemic or hemorrhagic)	4 (1.0%) [9]	1 (0.8%) [23]	0.85 (0.10–7.67)	0.89	6 (1.6%) [27]	2 (2.2%) [26]	1.33 (0.26–6.80)	0.73
Acute kidney injury	8 (1.9%) [8]	9 (7.5%) [19]	3.96 (1.54–10.24)	0.004	9 (2.3%) [27]	12 (11.1%) [22]	5.04 (2.11–12.09)	<0.001
Major arrhythmia	26 (6.2%) [8]	18 (14.8%) [18]	2.47 (1.36–4.48)	0.003	32 (8.0%) [27]	22 (20.3%) [21]	2.66 (1.55–4.58)	<0.001
Hospitalization for heart failure	3 (0.7%) [9]	4 (3.4%) [23]	4.65 (1.03–20.54)	0.04	18 (5.0%) [27]	5 (6.6%) [26]	1.27 (0.48–3.32)	0.63

Depicted are counts with the Aalen-Johanssen estimator of the cumulative incidence (%) [in square brackets the number of patients with the competing event occurring before the event of interest]. Subdistribution ratio of the hazards using the Fine & Grey methodology with 95% confidence interval (CI) and p-value comparing controls vs. cases.

^a First events of each event type under competing risk with death.