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. 2023 Jul 5;22(6):1815–1828. doi: 10.1007/s10237-023-01734-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Local myofiber mechanics (rows) in 4 subepicardial (a) and subendocardial (b) points (columns). From the top to bottom row, Cauchy stress in fiber direction and logarithmic strain as a function of time and stress–strain loops for a healthy heart, CMI5, CMI5wt and CMI5cf. The dotted lines mark the diastolic, isovolumic contraction, systolic and isovolumic relaxation phase, respectively. End-diastole and end-systole are marked with a $\circ$ and $◊$ respectively