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. 2023 Oct 28;13:18538. doi: 10.1038/s41598-023-45695-y

Table 1.

Characteristics of included studies.

Authors: countries Designs: aims Interventions: ways of distributing intervention Selected outcomes Major condition of study Settings Participant’s age Gender: Ethnicity Incomes
Meischke et al.23: USA RCT: To increase the use of emergency medical services via 911 calls and to reduce pre-hospital delay for individuals experiencing AMI symptoms The Direct mail intervention: Direct Mail/Telephone

- Calling 911 or EMS

- Time of delay/seeking

Mixed conditions (AMI/CAD patients & Normal People) Mixed setting (Hospital & Community)  ≥ 80% ≥ 60 years with no report mean age and a standard deviation Intervention group (n = 4,101) : male = 54.9 (2,251) , female = 46.1 (1,890) control group (n = 1,343) : male = 55.4 (744) , female = 44.6 (599) White: 92.3% vs. 91.6%, African American 4.1% vs. 5.2%, Asian: 3.2% vs. 2.9%, American Indian: 0.1% vs. 0%, Hispanic: 0.4% vs. 0.2% Intervention vs. Control groups < 20,000 = 35.4% vs. 31.0% 20,000–39,999 = 21.9% vs. 22.9% 40,000–49,000 = 20.2% vs. 19.2% 50,0000 = 22.6% vs. 26.9%
Hedges et al.24: USA RCT: To determine the impact of a communicating educational intervention to reduce patient delay time A community-based intervention program: Multiple Pathways (Face-to-Face/Home Visit & Advertisement)

- Mortality

- Awareness

Risk People Community  ≥ 80% ≥ 60 years with no report mean age and a standard deviation Intervention group male = 65.4 (1,104) female = 34.6 (589) control group male = 61.5(814) ,female = 38.5 (510) Mixed Not report
Luepker et al.25: USA RCT: To reduce patient delay from symptom onset to hospital presentation and increase emergency medical service (EMS) use The Rapid Early Action for Coronary Treatment (REACT) trial: Face-to-Face/Home Visit

- Calling 911 or EMS

- Time of delay/seeking

Mixed conditions (AMI/CAD patients & Normal People) Community  ≥ 80% ≥ 60 years with no report mean age and a standard deviation No report

Reference vs. Intervention groups

Black: 8.7% vs. 8.7%, White: 76.7% vs. 78%, Hispanic: 11.6% vs. 12.1%, and (other): 4.9% vs. 3.2%

Median household income: reference group = 29,896 (18,396–39,264), intervention group = 27,056 (15,890–32,842)
Meischke et al.26: USA RCT: To evaluate the effectiveness of the heart attack survival kit The Heart Attack Survival Kit: Multiple Pathways (Face-to-Face/Home Visit & Direct Mail/Telephone)

- Calling 911 or EMS

- Appropriate action/taking aspirin

Normal People Mixed setting (Hospital & Community) 100% ≥ 60 years with mean age of 73 and a standard deviation (SD) of 6.4 Male: 51% (n = 360), female 49% (n = 345) American Indian Income < 20,000 = 19%, 20,000–40,000 = 34%, 40,000–60,000 = 15%, > 60,000 = 7%
Meischke et al.27: USA RCT: To test an intervention designed to (a) call 911 and (b) take an aspirin in response to AMI symptoms The Heart Attack Survival Kit: Multiple Pathways (Face-to-Face/Home Visit & Direct Mail/Telephone)

- Knowledge

- Calling 911 or EMS

- Appropriate action/taking aspirin

Risk People Community 100% ≥ 60 years with mean age of 73 and a standard deviation (SD) 8.2 Intervention group: Male = 37%(65) ,female = 63%(111) Control group : male = 37%(54) ,female = 63%(93) Intervention vs. Control groups: white 95% (167) vs. 97% (143) and other 5% (9) vs. 3% (4) Intervention vs. Control groups < 24,000$ = 16% vs. 22%, 25,000–39,000$ = 14% vs. 28%, 40,000–54,999$ = 15% vs. 10%, > 55,000$ = 18% vs. 18%, (p = .003)
Lefler et al.28: USA Quasi-Experimental: To improve the accuracy of the perceived risk of MI perception, and increase knowledge of MI symptoms A structured/tailored educational/counseling intervention: Face-to-Face /Home Visit

- Knowledge

- Belief/attitude

Risk People Community 100% ≥ 60 years with no report mean age and a standard deviation 100% were female 85% (77) were Caucasian and 15% (13) others Classified two groups < 30,000$ and = or more than 30,000 but did not report the results
Meischke et al.29: USA RCT: To increase utilization of 911 and self-administration of aspirin for seniors experiencing chest pain The Heart Attack Survival Kit: Face-to-Face/Home Visit

- Calling 911 or EMS

- Appropriate action/taking aspirin

Risk People Community 100% ≥ 60 years with mean age of 78 and no report standard deviation The proportion of males (39% in control group and 42% in intervention group) Not report Not report
Tullmann et al.30: USA RCT: To investigate the effectiveness of educational and counseling intervention for older adults A structured/tailored educational/counseling intervention: Face-to-Face /Home Visit

- Knowledge

- Belief/attitude

- Calling 911 or EMS

- Coping behavior/Anxiety

AMI/CAD patients Community 100% ≥ 60 years with mean age of 74 and a standard deviation (SD) 6.0 Total : male = 48% (55) ,female = 52% (60), Control group : male = 51% (29), female = 49% (28) intervention group : male = 45%(26) ,female = 55% (32) White n = 83 (72%), African-American = 8 (7%), Hispanic = 14 (12%), Native American = 8 (7%), Asian/Pacific Islander = 1(1%), Other = 1(1%)  < $15,000 = 45%, $15,000 – $30,000 = 28%, $30,001 – $45,000 = 7%, $45,001 – $60,000 = 8%, > $60,000 = 9%
Kalman et al.31: USA Quasi-Experimental: To increase women's knowledge of female prodromal and myocardial infarction (Ml) symptoms and the appropriate response to these symptoms Health education-Matters Of Your Heart-using acronym FACTSS & CURB: Face to Face/Home Visit - Knowledge Risk People Community  ≥ 80% ≥ 60 years with mean age of 68 and no report standard deviation 100% women The majority of the sample was Caucasian n = 46(92%), African American n = 2(3.9%), Other n = 1(2%) Not report
Meisinger et al.32: Germany RCT: To evaluate the effects of nurse-based case management for elderly patients discharged after an AMI from a tertiary care hospital Nurse-based case management for elderly patients: Multiple Pathways (Face-to-Face/Home Visit & Direct Mail/Telephone)

- Mortality

- Readmission

- Time of delay/seeking

AMI/CAD patients Community 100% ≥ 60 years with mean age of 75.4 and a standard deviation (SD) 6.0 Total Male 62% (204), Intervention 62.7% (101)/Control 61.3% (103) Mixed Not report
Kirchberger et al.33: Germany RCT: To evaluate the nurse-based case management for elderly patients discharged from the hospital after an AMI Nurse-based case management for elderly patients: Multiple Pathways (Face-to-Face/Home Visit & Direct Mail/Telephone)

- Mortality

- Readmission

- Coping behavior/Anxiety

- Malnutrition risk

AMI/CAD patients Community 100% ≥ 60 years with mean age of 75.2 and a standard deviation (SD) 6.0 Total Male 62% (204), Intervention 62.7% (101)/Control 61.3% (103) Mixed Not report