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. 2023 Oct 28;14(10):706. doi: 10.1038/s41419-023-06228-7

Fig. 6. Loss of A3R impacts the gene expression of the muscle-derived CD45+ cells.

Fig. 6

A Single-cell analysis showing the expression of various adenosine receptors in CD45+ cells isolated from TA muscles of wild-type mice at day 4 post-CTX injury. 1. Resolution-related MΦs, 2. Growth factor-expressing MΦs, 3. Pro-inflammatory MΦs, 4. Antigen-presenting MΦs. 5. Neutrophils, 6. CD8a+ Clec9a+dendritic cells, 7. Fibroblasts, 8. Fibroblast-like cells, 9. Myeloid CD8a- dendritic cells, 10. Endothelial cells, 11. T cells, NK-T cells, 12. Lymphoid CD8a+ dendritic cells. B mRNA expressions of various adenosine receptors and inflammatory markers in muscle-derived CD45+ cells isolated at various time points post-CTX injury detected by RT-qPCR. Data are expressed as mean and individual values and statistical significance was determined by two-tailed Student’s t-test and ANOVA. *p < 0.05, **p < 0.01 (n = 4).