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. 2023 Oct 16;14:1231937. doi: 10.3389/fimmu.2023.1231937

Figure 1.

Figure 1

The landscape of PBMCs and kidney cells in NS-IgAN patients and healthy controls identified by single-cell transcriptomic analysis. (A) Schematic diagram of the study design for scRNA-seq. Con, n=3; NS-IgAN, n=3 (NGC, n=1; SGC, n=1; LGC, n=1); CTRL, n=3; HU-IgAN, n=4. (B) Distribution of 30 cell clusters in PBMCs. The figure on the left is a two-dimensional UMAP visualization of PBMCs. Different colors represent 30 clusters. The figure on the right is the percentage of each sample in each cell type. (C) Distribution of 16 cell types in kidney cells. The figure on the left is a two-dimensional UMAP visualization of kidney cells. Different colors represent 16 cell types. The figure on the right is the percentage of each sample in each cell type (D) Violin plot showing marker genes for each PBMC cell type. (E) Violin plot showing marker genes for each kidney cell type.