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. 2023 Mar 29;45(5):268–275. doi: 10.1159/000530389

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© 2023 S. Karger AG, Basel

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Fig. 3. — D-2PMPA stabilizes microglia process. a Sequential photomicrograph from time-lapse imaging of microglia stained with lectin. Sequential images of this microglia were processed to find the regions where microglia and its processes are changing for different periods of time. b CP kits from the same litter were randomly divided into 2 groups and received either saline or D-2PMPA (containing 20 mg/kg 2-PMPA) injection (i.v.) on PND1 and sacrificed 48 h post-injection. D-2PMPA treatment significantly improved microglial stability index to healthy control levels. c, d Neurolucida tracing of microglia revealed significant increase in microglia process ramification after D-2PMPA treatment. *p < 0.05.