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. 2023 Oct 30;18:810. doi: 10.1186/s13018-023-04275-6

Table 2.

Association between triglyceride-glucose index and bone mineral density among 3646 US adults

Variables Model 1 Model 2 Model 3 Model 4
β (%95 CI) β (%95 CI) β (%95 CI) β (%95 CI)
Lumbar bone bmd
TyG − 0.028 (− 0.035 ~ − 0.02) − 0.024 (− 0.031 ~ − 0.016) − 0.009 (− 0.017 ~ 0) − 0.008 (− 0.017 ~ 0)
Q1 0(Ref) 0(Ref) 0(Ref) 0(Ref)
Q2 0 (− 0.013 ~ 0.013) 0.002 (− 0.011 ~ 0.016) 0.013 (0 ~ 0.026) 0.014 (0.001 ~ 0.027)
Q3 − 0.022 (− 0.036 ~ − 0.009) − 0.018 (− 0.032 ~ − 0.005) 0.005 (− 0.009 ~ 0.019) 0.006 (− 0.008 ~ 0.02)
Q4 − 0.051 (− 0.064 ~ − 0.038) − 0.045 (− 0.059 ~ − 0.031) − 0.019 (− 0.034 ~ − 0.003) − 0.017 (− 0.033 ~ − 0.002)
P for trend  < 0.001  < 0.001 0.0096 0.0142
Total bmd
TyG − 0.002 (− 0.007 ~ 0.004) − 0.01 (− 0.016 ~ − 0.005) − 0.007 (− 0.013 ~ − 0.001) − 0.007 (− 0.012 ~ − 0.001)
Q1 0(Ref) 0(Ref) 0(Ref) 0(Ref)
Q2 0.007 (− 0.002 ~ 0.017) 0 (− 0.009 ~ 0.009) 0.002 (− 0.006 ~ 0.011) 0.003 (− 0.005 ~ 0.012)
Q3 0.008 (− 0.002 ~ 0.018) − 0.002 (− 0.011 ~ 0.008) 0.004 (− 0.005 ~ 0.014) 0.005 (− 0.004 ~ 0.015)
Q4 − 0.007 (− 0.017 ~ 0.002) − 0.023 (− 0.033 ~ − 0.013) − 0.017 (− 0.027 ~ − 0.007) − 0.015 (− 0.026 ~ − 0.005)
P for trend 0.1732 < 0.001 0.0039 0.007
Subtotal bmd
TyG 0.009 (0.004 ~ 0.015) − 0.005 (− 0.01 ~ − 0.001) − 0.006 (− 0.011 ~ − 0.001) − 0.005 (− 0.011 ~ 0)
Q1 0(Ref) 0(Ref) 0(Ref) 0(Ref)
Q2 0.016 (0.006 ~ 0.025) 0.003 (− 0.005 ~ 0.011) 0.003 (− 0.005 ~ 0.011) 0.004 (− 0.004 ~ 0.012)
Q3 0.021 (0.011 ~ 0.03) 0.004 (− 0.005 ~ 0.012) 0.006 (− 0.003 ~ 0.014) 0.006 (− 0.002 ~ 0.015)
Q4 0.012 (0.002 ~ 0.022) − 0.015 (− 0.024 ~ − 0.006) − 0.014 (− 0.023 ~ − 0.005) − 0.013 (− 0.023 ~ − 0.004)
P for trend 0.0081 0.002 0.0054 0.009

Model 1 was not adjusted. Model 2 was adjusted for age and gender. Model 3 was adjusted for all covariables in model 2 plus race education, moderate recreational activities, diabetes, uric acid, total calcium, serum phosphorus, waist circumference, low-density lipoprotein cholesterol, smoke status, 25-hydroxyvitamin D(25OHD). Model 4 was adjusted for all covariables in model 3 plus antihyperlipidemic agents

TyG Triglyceride-glucose index, CI Confidence interval, Ref Reference