Table 1.
Results showing SNPs with GWAS level of significance (P < 5 × 10−8) from the genetic association analysis comparing men and women with Behçet’s disease in the Turkish cohort.
| MAF Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Locus | Chr | SNP | Male | Female | OR | 95% CI LL | 95% CI UL | P-value |
| HLA-B/MICA | 6 | rs2848712 | 0.41 | 0.33 | 1.46 | 1.28 | 1.66 | 1.22 × 10−8 |
| HLA-B/MICA | 6 | rs2596527 | 0.41 | 0.33 | 1.46 | 1.28 | 1.66 | 1.22 × 10−8 |
| HLA-B/MICA | 6 | rs2848713 | 0.41 | 0.33 | 1.46 | 1.28 | 1.66 | 1.22 × 10−8 |
| HLA-B/MICA | 6 | rs77563643 | 0.41 | 0.33 | 1.45 | 1.27 | 1.65 | 2.47 × 10−8 |
| HLA-B/MICA | 6 | rs3819272 | 0.41 | 0.33 | 1.44 | 1.27 | 1.64 | 3.15 × 10−8 |
| HLA-B/MICA | 6 | rs79953803 | 0.41 | 0.33 | 1.43 | 1.26 | 1.63 | 4.30 × 10−8 |
SNP, single nucleotide polymorphism; MAF, minor allele frequency; OR, odds ratio of male compared to female patients (case-case analysis); CI LL, confidence interval lower limit; CI UL, confidence interval upper limit; P-value, P-values from the logistic regression analysis.