Figure 4.

pH-activatable cancer theranostics. A) pH-induced aggregation of a porphyrin-peptide-based nanofiber via protonation for PDT and fluorescent imaging-aided prognosis. a) Schematic illustration. b) Fluorescence images of the mice at various time points post-injection. Reproduced with permission ¹³². Copyright 2022 the Authors, published by Wiley-VCH. B) An activatable polymer-coated ternary alloy for MRI and ferroptosis therapy. a) Schematic design to illustrate that the detachment of activatable polymer coatings could promote release of metal ions in the core of the nanomedicine. b) T1-weighted MR images of R-PtWMn with different concentrations at different pH values. c) Tumor growth curves after the treatment with the polymer-coated alloy and controls. Reproduced with permission ¹³³. Copyright 2022, Wiley-VCH.