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[Preprint]. 2023 Oct 17:2023.10.16.562508. [Version 1] doi: 10.1101/2023.10.16.562508

Figure 3: IHC of fibrinogen and CD31 expression in hippocampus after intranasal LPS or saline:

Figure 3:

12-week-old C57B/6 mice received intranasal LPS described in Figure 2, followed by sacrifice 24hr after the last dose of LPS or saline. Brains were removed and processed for IF. Red (CD31+), Green (Fibrinogen). Scale bar = 16μm (A). Fibrinogen intensity over intensity over field-of-view (B), Extravascular fibrinogen volume (C) and intensity (D) over CD31+ volume quantified. Values presented as mean ± SEM (saline n=3; 6h LPS n=4; 24h LPS n=4; 72h LPS n=4). **p<0.01, ****p<0.0001. Analyses were performed as One-way ANOVA with post-hoc analysis: p<0.05(*), p<0.01(**), p<0.001(***), p<0.0001(****).