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[Preprint]. 2023 Oct 17:2023.10.16.562516. [Version 1] doi: 10.1101/2023.10.16.562516

Figure 3. Sibling contributions to hematopoiesis-derived cells diverge between blood and brain.

Figure 3.

(A)-(E) Chimerism fractions in brain and blood of three animals. CJ028 was part of a triplet litter, and the contribution of each sibling is shown in a separate panel (D,E). Red horizontal lines: twin contribution to blood cells as ascertained from whole-genome sequencing of whole-blood-derived genomic DNA (Census-seq). Blue horizontal lines: total twin contribution to blood cells as estimated from PBMC snRNA-seq (all cells). Vertical bars: binomial confidence interval (95%). Numbers in fraction: number of sibling cells over total cells in the cell type. glia+endothelia: astrocytes, oligodendrocytes, polydendrocytes, ependymal cells, endothelial cells.