Figure 4. XR-seq identifies intergenic transcription-coupled repair, in high concordance with intergenic transcription identified by capped RNA-seq.

For the 85,418 intergenic bins, we identified regions with non-zero read counts by short- or long-capped RNA-seq, RNA-seq, (6–4)PP XR-seq, and CPD XR-seq, respectively. We require non-zero read counts to be detected in both (A) or either replicate (B) and report the overlapping results separately.