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[Preprint]. 2023 Oct 16:2023.10.15.23296448. [Version 1] doi: 10.1101/2023.10.15.23296448

Figure 5: Associations of blood cell trait polygenic scores (PGS) with tumor immune microenvironment (TIME) features in TCGA.

Figure 5:

Associations for selected blood cell trait PGS with heritable tumor immune microenvironment features identified in TCGA by Sayaman et al. (2021). Heterogeneity in PGS effect on specific TIME features between IDH-mutated and IDH-wildtype tumors was tested using Cochran’s Q test. Beta coefficients for Enrichment Score (ES) phenotypes were estimated per 10-unit change.