ELISA of inflammatory cytokines profile in the serum. The local administration of CB-MDSC significantly decreased production of IFN-γ (A), IL-17 (B), IL-1β (C), and TNF-α (D) in the serum, compared with those of the PBS-treated groups. The serum was quantified by ELISA on day 21, and naive groups have obviously low expression comparison with PBS-treated groups. Data are presented as mean ± SD. Comparison between the three groups was expressed using one-way ANOVA with post hoc paired Tukey's test (n = 5; *P < 0.05; **P < 0.01; and ***P < 0.001).