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Effect of the H/N-Ras inhibitor FTI-277 on transformation of RK3Ea
| Transfected DNA | No. of foci with:
|
|
|---|---|---|
| 0 μM FTI-277 | 5 μM FTI-277 | |
| None | 0 | 0 |
| pcDNA3.1 | 0 | 0 |
| v-mos | 848 | 676 |
| H-ras | 56 | 0 |
| pCMV3ΔGP | 908 | 516 |
The effect of FTI-277 on transformation in RK3E cells was assayed under the focus-forming conditions described for Table 4.
