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. 2023 Oct 27;7(11):e977. doi: 10.1097/HS9.0000000000000977

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Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Hematology Association.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 8. — Interactions of CD8⁺ effector memory T cells and memory B cells with HSCs and CD4⁺ T cells. (A) Cellular interactions between CD8⁺ EM T cells and HSCs in healthy controls and AA patients. (B) Cellular interactions between CD8⁺ EM T cells and HSCs in IST responders and non-responders. (C) Cellular interactions between memory B cells (memory B) and CD4⁺ T cells (CD4⁺ T) in healthy controls and AA patients. (D) Cellular interactions between memory B cells and CD4⁺ T cells (CD4⁺ T) in IST responders and non-responders. AA = aplastic anemia; CD8+ EM = CD8+ effector memory; HSC = hematopoietic stem cell; IST = immunosuppressive therapy.