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. 2023 May 25;38(11):2444–2455. doi: 10.1093/ndt/gfad112

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© The Author(s) 2023. Published by Oxford University Press on behalf of the ERA.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3: — Broad schematic to support clinical use of SGLT2i in as foundational therapy for CKD considering need for specific treatment in both cardiometabolic and glomerular disease. CKD: chronic kidney disease; eGFR: estimated glomerular filtration rate (eGFR); FSGS: focal segmental glomerulosclerosis; DM: type 2 diabetes mellitus; SGLT2i: sodium-glucose cotransporter-2 inhibitor; uACR: urine albumin-creatinine ratio; ASCVD: atherosclerotic cardiovascular disease; RASi renin-angiotensin system inhibition.