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. Author manuscript; available in PMC: 2023 Oct 31.
Published in final edited form as: Matrix Biol. 2016 Nov 15;62:40–57. doi: 10.1016/j.matbio.2016.11.003

Figure 4.

Figure 4.

Regulation of HA homeostatic marker gene expression by exogenous TGFβ1, its inhibitors, biomechanical strain and aging in cultured porcine aortic VICs as measured by qRT-PCR. Gene expression (on y-axis) is presented as relative log2 expression, and all data for each gene is normalized to young, static with no treatment. “None”, no treatment; “T+S”, TGFβ1 + SB431542; “T+U”, TGFβ1 + U0126; “S+U”, SB431542 + U0126; “All”, TGFβ1 + SB431542 + U0126. #, vs. none, p<0.05; *, vs. none, p<0.001; &, vs. T, p<0.001; ^, vs. young, p<0.0001. Another version of the same figure with more elaborate statistics is provided as Supplemental Fig 4.