FIG. 3.

IFN-dependent regulation of SeV-induced genes. Select SeV-regulated genes display differential induction patterns in wt (2fTGH) and Jak1^−/− (U4C) cells. (A) Microarray data showing average increase (n-fold) in mRNA expression 6 h after SeV infection in 2fTGH and U4C cells. Genes are grouped based on their independence of, dependence on, or impairment by Jak1 for induction. (B) RPA (A20) and Northern (OAS, p69) analysis of mRNA expression in 2fTGH and U4C cells, before or 6 h after SeV infection.