TABLE 2.
Genes induced or repressed by SeV infection in various cell linesa
Encoded protein | Unigene ID | Symbol | Effect of SeV infection in:
|
||||
---|---|---|---|---|---|---|---|
2fTGH | U4C | 2F-SR | P2.1 | U4C.2 | |||
2′-5′-oligoadenylate synthetase 2 (69-71 kDa) | Hs.414332 | OAS2 | I | U | U | R | U |
Activating transcription factor 3 | Hs.460 | ATF3 | I | I | U | I | I |
Apoptosis inhibitor | Hs.75263 | cIAP1 | I | I | U | I | U |
Apoptosis inhibitor 2 | Hs.127799 | cIAP2 | I | I | U | U | U |
Bcl-2 binding component 3 | Hs.87246 | BBC3 (PUMA) | I | I | U | U | I |
Chemokine (C-X-C motif) ligand 10 | Hs.2248 | IP-10 (CXCL10) | I | I | U | I | I |
Colony-stimulating factor 1 (macrophage) | Hs.173894 | CSF1 | I | I | U | I | I |
Fibroblast growth factor 2 (basic) | Hs.284244 | FGF2 | I | U | I | U | U |
Fucosyltransferase 2 | Hs.292999 | FUT2 | I | I | I | I | I |
General transcription factor IIF, polypeptide 1 | Hs.68257 | GTF2F1 | I | U | U | U | U |
GTP cyclohydrolase 1 (dopa-responsive dystonia) | Hs.86724 | GCH1 | I | U | U | U | U |
IFN-induced protein with tetratricopeptide repeats 1 | Hs.20315 | ISG56 | I | I | I | U | I |
IFN-induced protein with tetratricopeptide repeats 2 | Hs.293797 | ISG54 | I | I | I | U | I |
IFN-induced protein with tetratricopeptide repeats 4 | Hs.181874 | ISG60 | I | U | U | U | U |
Inhibin, beta A (activin A, activin AB alpha polypeptide) | Hs.727 | INHBA | I | I | U | U | U |
Inhibitor of kappa B alpha | Hs.81328 | IκBα | I | I | U | I | I |
Interferon regulatory factor 1 | Hs.80645 | IRF-1 | I | I | U | U | U |
Interferon regulatory factor 2 | Hs.83795 | IRF-2 | I | U | U | U | U |
Interferon, alpha-inducible protein (clone IFI-15K) | Hs.833 | ISG15 | I | I | I | U | I |
Interleukin 6 | Hs.93913 | IL-6 | I | I | U | U | I |
Interleukin 8 | Hs.624 | IL-8 | I | I | U | I | I |
Jun B proto-oncogene | Hs.515157 | JUNB | I | I | U | I | U |
Macrophage inflammatory protein I alpha | Hs.73817 | MIP1α (CCL3) | I | I | U | I | I |
Mannose-binding lectin (protein C) 2 | Hs.2314 | MBL2 | I | I | R | I | I |
MHC class I, A | Hs.181244 | HLA-A | I | U | I | U | I |
MHC class I, C | Hs.277477 | HLA-C | I | U | U | I | I |
MHC class I, F | Hs.110309 | HLA-F | I | U | U | U | I |
MHC class I, G | Hs.73885 | HLA-G | I | U | U | U | I |
Monocyte chemotactic protein 1 | Hs.303649 | MCP1 (CCL2) | I | U | U | U | U |
Natural killer cell transcript 4 | Hs.943 | NK4 | I | U | U | U | I |
Nexin, plasminogen activator inhibitor type 1 | Hs.82085 | PAI1 (SERPINE1) | I | I | I | I | I |
NF-κB p105 | Hs.83428 | NF-κB1 | I | I | U | I | I |
Nuclear factor (erythroid-derived 2)-like 3 | Hs.22900 | NFE21.3 (NRF3) | I | I | U | I | U |
Nucleoside phosphorylase | Hs.75514 | NP | I | U | I | U | I |
Phorbol-12-myristate-13-acetate-induced protein 1 | Hs.96 | NOXA (PMAIP1) | I | I | I | I | I |
Protein tyrosine phosphatase, nonreceptor type 11 | Hs.83572 | PTPN11 (SHP2) | I | I | U | U | I |
Protein tyrosine phosphatase, receptor type kappa | Hs.79005 | PTPRK | I | U | U | U | U |
Short stature homeobox | Hs.105932 | SHOX | I | U | U | U | I |
Similar to S. cerevisiae SSM4 | Hs.380875 | TEB4 | I | I | I | I | U |
Stanniocalcin | Hs.25590 | STC1 | I | I | I | U | U |
Syndecan 4 (amphiglycan, ryudocan) | Hs.252189 | SDC4 | I | I | U | I | I |
Tight junction protein 2 (zona occludens 2) | Hs.75608 | TJP2 | I | I | I | I | I |
TNF receptor-associated factor 1 | Hs.2134 | TRAF1 | I | I | R | U | U |
Transcription factor AP-2 gamma | Hs.61796 | ERF1 (TFAP2C) | I | U | U | I | U |
Tumor necrosis factor alpha-induced protein 3 | Hs.211600 | TNFAIP3 (A20) | I | I | U | I | I |
UDP-N-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 | Hs.130181 | GALNT2 | I | U | I | U | U |
Vascular endothelial growth factor C | Hs.79141 | VEGFC | I | I | I | U | U |
Viperin | Hs.17518 | CIG5 | I | U | I | U | I |
Zinc finger CCCH type, antiviral 1 | Hs.35254 | ZC3HAV1 | I | I | I | U | U |
I, induced; U, unchanged; R, repressed.