FIG. 8.

Ultrastructure of the BFA-induced accumulation of virus structures in the cytoplasm of infected neurons. Dissociated rat SCG neurons were infected with PRV 180 at a high MOI followed by incubation for 12 h (A), treatment with 2 μg of BFA/ml from 2 to 12 h postinfection (B) or treatment with BFA as before with recovery from 12 to 18 h postinfection (C) prior to fixation and processing for transmission electron microscopy. For each sample, a region of the neuronal cell body (left, white box) is shown at a higher magnification (right). N indicates the nucleus.