FIG. 9.

Enveloped virus particles are restricted from axons following the BFA treatment of infected neurons. Dissociated rat SCG neurons were infected with PRV 180 at a high MOI followed by incubation for 12 h (A) or treatment with 2 μg of BFA/ml from 2 to 12 h postinfection (B) prior to fixation and processing for transmission electron microscopy. A proximal region (A) or more distal region (B) of the axonal projection (left, white box) is shown at a higher magnification (right).