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. Author manuscript; available in PMC: 2023 Oct 31.
Published in final edited form as: J Neonatal Perinatal Med. 2023;16(3):527–537. doi: 10.3233/NPM-230084

Table 2:

NEC features in infants with severe WMI and non-severe WMI

Variable N Overall Mild/noWMI Moderate/Severe WMI P-Value
N=67 N=48 N=19
Clinical presentation, n (%) 59 0.78
 Abdominal Distension 54 (91.5%) 38 (92.7%) 16 (88.9%)
 Bloody Stools 3 (5.1%) 2 (4.9%) 1 (5.6%)
 Feeding Intolerance 2 (3.4%) 1 (2.4%) 1 (5.6%)
Pneumatosis 59 22 (37.3%) 14 (34.1%) 8 (44.4%) 0.45
Pneumoperitoneum 59 35 (59.3%) 23 (56.1%) 12 (66.7%) 0.45
Portal Venous Gas 59 2 (3.4%) 1 (2.4%) 1 (5.6%) 0.52
Age of NEC Onset (days), median (IQR) 25 8 (6, 23) 7 (5, 16) 8 (7, 34) 0.32
Fulminant NEC, n (%) 59 4 (6.8%) 4 (9.8%) 0 (0.00%) 0.30
Presence of Penrose Drain, n (%) 57 25 (43.9%) 18 (45.0%) 7 (41.2%) 0.80
Surgery < 48 Hours, n (%) 59 40 (67.8%) 29 (70.7%) 11 (61.1%) 0.47
Length of Bowel Resected (cm), median (IQR) 59 12.7 (3.7, 28.8) 10.4 (3.7, 28) 15.7 (9.0, 28.8) 0.56
Region of Bowel Resected, n (%) 54 0.18
 Small Bowel Resected 35 (64.8%) 27 (71.1%) 8 (50.0%)
 Large bowel resected 2 (3.7%) 2 (5.3%) 0 (0.00%)
 combined large and Small Bowel Resected 17 (31.5%) 9 (23.7%) 8 (50.0%)
Presence of Ileocecal Valve, n (%) 58 45 (77.6%) 34 (82.9%) 11 (64.7%) 0.17
Surgical Morbidity (Infection, Adhesions, Strictures, Dehiscence), n (%) 67 23 (34.3%) 13 (27.1%) 10 (52.6%) 0.047
Single Surgical Morbidity (Infection, Adhesions, Strictures, Dehiscence), n (%) 67 15 (22.4%) 8 (16.7%) 7 (36.8%) 0.11
More than One Surgical Morbidity (Infection, Adhesions, Strictures, Dehiscence), n (%) 67 7 (10.4%) 4 (8.3%) 3 (15.8%) 0.40
Adhesions, n (%) 67 9 (13.4%) 7 (14.6%) 2 (10.5%) 0.99
Wound Dehiscence, n (%) 67 8 (11.9%) 3 (6.3%) 5 (26.3%) 0.036
Wound Infection, n (%) 67 3 (4.5%) 1 (2.1%) 2 (10.5%) 0.19
Stricture, n (%) 67 5 (7.5%) 4 (8.3%) 1 (5.3%) 0.99
Fistula, n (%) 67 3 (4.5%) 1 (2.1%) 2 (10.5%) 0.192
Compartment Syndrome, n (%) 67 1 (1.5%) 1 (2.1%) 0 (0.00%) 0.99
Short Bowel Syndrome, n (%) 50 29 (58.0%) 19 (54.3%) 10 (66.7%) 0.416