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. 2023 Oct 3;12(5):990–997. doi: 10.1093/toxres/tfad093

Table 4.

The area under the curve, cut-off values, sensitivity, specificity, negative predictive value, and positive predictive value & pairwise comparison of scoring systems for prediction of ICU admission.

Outcome ICU admission
Scores REMS MEWS SCS
AUC 0.891 0.877 0.960
95% CI of AUC 0.798 to 0.984 0.779 to 0.974 0.912 to 1.000
P-value <0.001a <0.001a <0.001a
Cut-off >3 >4 >7
Sens (%) 78.6 85.7 92.9
Spec (%) 81.8 70.5 90.9
PPV (%) 57.9 48.0 76.5
NPV (%) 92.3 93.9 97.6
Accuracy (%) 81.0 74.1 91.4
Pairwise comparisons of AUCs REMS vs. MEWS = 0.678
REMS vs. SCS = 0.112
MEWS vs. SCS = 0.015a

AUC: area under the curve; ICU: intensive care unit; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; REMS: rapid emergency medicine score; SCS: simple clinical score; MEWS: Modified Early Warning Score; P-values are based on the Mann-Whitney test.

aSignificant at p < 0.05.