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. 2023 Oct 3;12(5):990–997. doi: 10.1093/toxres/tfad093

Table 5.

The area under the curve, cut-off values, sensitivity, specificity negative predictive value, and positive predictive value & pairwise comparison of scoring systems for predicting mechanical ventilation (Total n = 58).

Outcome Mechanical Ventilation
Scores REMS MEWS SCS
AUC 0.964 0.996 0.982
95% CI of AUC 0.912 to 1.000 0.983 to 1.000 0.950 to 1.000
P-value <0.001a <0.001a <0.001a
Cut-off >6 >8 >11
Sens (%) 100.0 100.0 100.0
Spec (%) 91.1 98.2 96.4
PPV (%) 28.6 66.7 50.0
NPV (%) 100.0 100.0 100.0
Accuracy (%) 91.4 98.3 96.6
Pairwise comparisons of AUCs REMS vs. MEWS = 0.130
REMS vs. SCS = 0.152
MEWS vs. SCS = 0.218

AUC: area under the curve; ICU: intensive care unit; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; REMS: rapid emergency medicine score; SCS: simple clinical score; MEWS: Modified Early Warning Score; P-values are based on the Mann-Whitney test.

aSignificant at p < 0.05.