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. Author manuscript; available in PMC: 2024 Nov 6.
Published in final edited form as: Angew Chem Int Ed Engl. 2023 Sep 27;62(45):e202312519. doi: 10.1002/anie.202312519

Scheme 2.

Scheme 2.

A) Proposed oxygen-dependent mechanism of ADLumin-4 for chemiluminescence generation.[3a, 25] B) Reaction mechanism and photoreaction of diazirines. C) The synthetic route for CRANAD-147, the designed photo-labile curcumin-diazirine analogue with two conjugated parts: the modified curcumin as the Aβ binding moiety and the aryl diazirine as the photosensitive moiety.