TABLE 6.
Adr1 affects Cat8 binding at weak CSREs
| Gene | Cat8 binding to promoter in Δadr1 | CSRE sequences (from furthest upstream to closest to ATG)a |
|---|---|---|
| ACS1 | Yes | GCCGTTCGTCCG (1) |
| TCCATTTCGCCG (1) | ||
| ADH2 | Reduced | TCCGTCTCTCCGG (2) |
| GCCGGAACACCG (4) | ||
| GCCTTGTGGCCC (2) | ||
| ADY2 | Yes | TCCGGAGCTCCG (3) |
| ACCACTCAGCCG (1) | ||
| GCCGCCCAACCG (3) | ||
| ATO3 | Reduced | GCCGCACCGCCG (4) |
| FBP1 | Yes | TCCATCCGTCCG (1) |
| TCCGGGTGTCCG (2) | ||
| ICL1 | Yes | TCCATTCATCCG (0) |
| JEN1 | Yes | TCCACTAGACCG (1) |
| MLS1 | Yes | TCCATTGAGCCG (0) |
| TCCATTGGGCCG (0) | ||
| CCCGGCGAGCCG (2) | ||
| GCCGGCTCGCCGG (4) | ||
| MDH2 | Yes | TCCATTTGGCCG (0) |
| CCCTTTAATCCG (0) | ||
| CCCATTCGGCCG (0) | ||
| PUT4 | Yes | TCCGGCAGCCCG (3) |
| CCCGGGTACCCG (3) | ||
| CCCGGGCTGCCG (3) |
a
Values in parentheses are the number of mismatches to consensus (see reference 38). Sequence portions in italics are mismatches that allowed in vitro binding; portions in boldface are mismatches that severely reduced in vivo binding.