Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Oct 30;14:6902. doi: 10.1038/s41467-023-42558-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — A Novel genes separate into five clusters with distinct expression patterns across human preimplantation development (n = 1402 genes in early cluster, 1391 genes in 2C cluster, 712 genes in 4C cluster, 987 genes in 8C cluster, 746 genes in late cluster). B Predicted coding probability for novel genes in each cluster defined in A. C Heatmap displaying the percentage of novel genes in each cluster containing distinct classes of human retrotransposons. D Heatmap displaying predicted transcription factor regulators of each novel gene cluster, including their DNA binding motifs (p-values calculated using HOMER findMotifsGenome.pl, q-values adjusted using Benjamini-Hochberg method). E Network diagram displaying predicted TFs-novel target gene pairs, as determined by integration of ATAC-Seq footprinting and inferred TF activity-gene expression correlation. For the box plot in B, box limits extend from the 25th to 75th percentile, while the middle line represents the median. Whiskers extend to the largest value no further than 1.5 times the inter-quartile range (IQR) from each box hinge. Points beyond the whiskers are outliers. Source data are provided as a Source Data file.