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Mean visual analogue pain score (VAS) in the Yang 2016 trial of vertebroplasty which was the primary outcome. All patients had fracture duration of less than 3 weeks. The vertical bars represent 95% confidence intervals. Results favoured vertebroplasty over conservative care at all time points to 12 months. This trial represents open-label randomised trial data of early vertebroplasty within 3 weeks of fracture
