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. 2023 Oct 30;13:18644. doi: 10.1038/s41598-023-45517-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Phylogenetic analyses of the 5,724 SARS-CoV-2 genomes sequenced from the COVID-19 deceased patients worldwide. (A) A detailed phylogenetic tree presenting all the significant clades associated with deceased COVID-19 patients. (B) Value of the entropy change (distribution of mutational frequency overall the SARS-CoV-2 genome) throughout the SARS-CoV-2 genome based on mutation count for each position. The maximum-likelihood tree was generated using Nextclade Web 2.14.1 web-based tool (https://clades.nextstrain.org/results; accessed on October 10, 2023).