Table 2.
Most frequent amino acid (AA) mutations predicted at various loci of SARS-CoV-2 genome obtained from deceased COVID-19 patients of the five continents.
| Continent | Loci of SARS-CoV-2 genome | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| S | ORF1a | ORF1b | M | N | ORF3a | ORF7a | ORF7b | ORF8 | ORF9b | |
| ASIA |
D614G P6081R A570D, N501Y D405N |
P3142 S1188L A1708D T265 I |
P314L P1000L A1918V P10S |
I82T A63T |
G204R P13L, D3L T205 I D377Y |
S26L T223 I |
82A T120I |
T40I |
L118V G8R |
T60A A11V |
| NORTH AMERICA |
D614G T478K G142D T1027 I S375F |
V2930L A2710T P3395H T3255 I |
G662S A1918V R1315C I1566V P314L |
I82T Q19E A63T |
S413R R203K R203M D63G D377Y |
S26L |
T120I V82A |
V21F |
V99L Y31F |
G38V |
| EUROPE |
D614G L452R N501Y K417T D405N |
T3255I P314L T3750I G1307S |
P1000L G662S E1264D I1566V P10S |
I82T Q19E D3G |
P13L R203K, D3L G215C P80R G204R |
T223I S26L |
V82A |
L32F M1V |
R101C A65G |
P3H |
| AFRICA |
D614G D950N E484K N501Y P681H |
P1640L T3750I K1655N T265I T1001I |
P314L A1918L R1315C P314L E1264D |
Q19E I82T |
G204R D63G S235F D377Y T205I |
S26L |
T120I V82A |
T40I | G96S | G38R |
| SOUTH AMERICA |
D614G L452R P681H D405N T478K |
T3255I K1795Q K856R P314L S135R |
G662S P1000L E1264D T2163I R135C |
A63T D3G |
S413R D3L G215C D377Y |
S26L T2231 ORF-3a |
T120I | H42Y | T26I | L64F |
Amino acid (AA) mutations occurred more than two continents are highlighted[bold].