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. 2023 Oct 14;26(11):108170. doi: 10.1016/j.isci.2023.108170

Figure 1.

Figure 1

Increased high-mannose glycans and decreased MAN1A1 in the decidual tissues of miscarriage patients

(A) Analysis of differential mannose-specific lectins in the bar graph. GNA: Galanthus nivalis lectin.

(B and C) Lectin blot and immunohistochemical staining analysis of high-mannose glycans in the decidual tissues of early pregnant women (n = 7) and miscarriage patients (n = 7).

(D) Schematic diagram of mannosyltransferases (ALGs) and mannosidases (MANs) catalyzing N-glycosylation synthesis by BioRender.

(E) qPCR analysis of ALGs and MANs in the decidual tissues of early pregnancy and miscarriage.

(F and G) Western blot and immunohistochemical staining analysis of MAN1A1 in the decidual tissues of early pregnant women and miscarriage patients. Scale bars, 20 μm ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.