REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-IGFBP-1	Affinity	Cat# DF1730; RRID: AB_2839084
Anti-PRL	Affinity	Cat# DF6506; RRID: AB_2838468
Anti-MAN1A1	Abcam	Cat# ab102797; RRID: AB_10860970
Anti-SP1	Proteintech	Cat# 21962-1-AP; RRID: AB_10898171
Anti-NPM1	Proteintech	Cat# 10306-1-AP; RRID: AB_2155163
Anti-GAPDH	Bioworld Biotech	Cat# AP0063; RRID: AB_2651132
Critical commercial assays
Lectin Microarray	Raybiotech	GA-Lectin 70
BCA Protein Assay Kit	Beyotime	P0012S
Prime Script RT reagent kit	Takara	RR037A
SYBR Premix Ex Taq II kit	Takara	DRR041A
RNA pull-down kit	Bersin BIO	Bes5102
Magna RIP kit	Millipore	17-700
Magna ChIP kit	Millipore	17-70085
RNA FISH SA-biotin	Gene Pharma	N/A
PARIS™ kit	Invitrogen	N/A
Experimental models: Cell lines
HESCs	ATCC	BFN608006424
Chemicals, peptides, and recombinant proteins
medroxyprogesterone 17-acetate (MPA)	Selleck	S256702
dibutyryl cAMP (dbcAMP)	Selleck	S785811
Golgi-Tracker Red	Beyotime	C1043
GNA	Vector Lab	Cat# L-1240-5; RRID: AB_2336471
Software and algorithms
ImageJ	National Institutes of Health	https://imagej.nih.gov/ij/
GraphPad Prism 9.0	GraphPad Prism Software	https://www.graphpad.com/
ImageLab	Bio-Rad Laboratories	https://chameleonimagelab.com/
Oligonucleotides
sense: 5′-GAGACUGACUCAUGAUCCATT-3′ antisense: 5′-UGGAUCAUGAGUCAG UCUCTT-3′	GenePharma	MAN1A1-siRNA
sense: 5′-GGUGUUAUCAAGUGAAUUATT-3′ antisense: 5′-UAAUUCACUUGAUAACA CCTT-3′	GenePharma	lncNEAT1-siRNA
sense:5′-CCAUUAACCUCAGUGCAUUTT-3′ antisense: 5′-AAUGCACUGAGGUUA AUGGT T-3′	GenePharma	SP1-siRNA
sense: 5′-GUGCAAAGGAUGAGUUGCATT-3′ antisense: 5′-UGCAACUCAUCCUUUG CACTT-3′	GenePharma	NPM1-siRNA
5′-AAGTTCGTGCTGCTGCTGGTATTC-3′	Sangon Biotech	MAN1A1-F
5′-TTGGAGGAGTCTGGCAGGAAGAAG-3′	Sangon Biotech	MAN1A1-R
5′-TGGCTAGCTCAGGGCTTCAG-3′	Sangon Biotech	LncNEAT1-F
5′-TCTCCTTGCCAAGCTTCCTTC-3′	Sangon Biotech	LncNEAT1-R
5′-TATGATGGCTCGAAGGCTCT-3′	Sangon Biotech	IGFBP-1-F
5′-CCATTCTTGTTGCAGTTTGG-3′	Sangon Biotech	IGFBP-1-R
5′-TCTCGCCTTTCTGCTTATTATAAC-3′	Sangon Biotech	PRL-F
5′-CGATTCGGCACTTCAGGAGCTT-3′	Sangon Biotech	PRL-R
5′-TCCTGTTCGACAGTCAGCCGCAT-3′	Sangon Biotech	GAPDH-F
5′-TGCAAATGAGCCCCAGCCTTCTCCA-3′	Sangon Biotech	GAPDH-R
5′-AAAAAAGTCCTAAGCAAGCACAGAA-3′	Sangon Biotech	MAN1A1-F (ChIP)
5’-GAAGCGGCAGGCAGAGTTC-3′	Sangon Biotech	MAN1A1-R (ChIP)
5′-TGAGTTCTGTTGTCTCGATTTCTTT ATACCTTTTGGTTTCCTTGGACATTT TTTTCAATCAGGA-3′	GenePharma	lncNEAT1 probe