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. 2023 Sep 17;5(11):100724. doi: 10.1016/j.xkme.2023.100724

Table 2.

Features used to distinguish lupus nephritis from pre-eclampsia23,24

Features Lupus Nephritis Pre-eclampsia
Onset Anytime during pregnancy After 20 wk of pregnancy
Hypertension Maybe present or absent Present
Extrarenal SLE signs and symptoms Present Absent
Serum uric acid levels <4.9mg/dL (low or normal) >4.9mg/dL (high)
Complement levels Maybe decreased or normal Normal
Anti ds-DNA levels Increased Normal
Active urinary sediments Present Absent
Urinary calcium excretion >195 mg/day <195 mg/day
sFlt-1/PlGF ratio24 Normal Increased

Abbreviations: SLE, systemic lupus erythematosus; DNA, deoxyribonucleic acid; sFlt-1, soluble fms-like tyrosine kinase 1; PlGF, placental growth factor.