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. 2023 Aug 1;31(6):640–647. doi: 10.4062/biomolther.2023.085

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Copyright © 2023, The Korean Society of Applied Pharmacology

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 8 — Effects of LFRGE intake on wrinkle formation in UVB-irradiated hairless mice. (A) Photographs of dorsal skin of hairless mice after UVB irradiation/no irradiation. The UVB irradiation dose is 80 mJ/cm², and after oral administration of 15 mg/kg.b.w./day as GABA of LFRGE, the skin wrinkles are significantly improved under the naked eye. (B) Skin Visiometer SV600 software analysis results of skin wrinkle data. n=10, ^###p<0.001 compared with normal mice, ***p<0.001 compared with UVB-irradiated mice.