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. 2015 Jun 1;2015(6):CD009566. doi: 10.1002/14651858.CD009566.pub2

Davies 1993.

Methods Parallel‐group RCT
Participants 95 participants recruited with allergic conjunctivitis
Interventions Three treatment arms: levocabastine 0.5 mg/ml; sodium cromoglycate 20 mg/ml; placebo eye drops. Duration of treatment 28 days
Outcomes Investigators' and participants' assessment of ocular symptoms (4‐point qualitative scale: excellent, good, moderate, poor)
Time points: at baseline, day 14 and 28 after treatment
Country United Kingdom
Number randomised, gender (male:female) 95 participants randomised. M:F 40:49
Age mean (SD), median, range Mean (range) levocabastine 30 years (7‐66); sodium cromoglycate 31 years (10‐69); placebo 30 years (13‐61)
Notes Not reported when study was conducted. Source of funding not stated. Declaration of interest by the authors was not stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk The method used to generate the allocation sequence was not described.
Allocation concealment (selection bias) Unclear risk The method used to conceal the allocation sequence was not described.
Incomplete outcome data (attrition bias) 
 All outcomes High risk Percentages given (numerators/denominators unclear)
Selective reporting (reporting bias) High risk P values given for selected outcomes
Other bias Unclear risk No apparent evidence of other risk of bias
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Double‐masked (p.520 ‐ methods): "…95 patients participated in this double‐blind, parallel group trial."
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Double‐masked (p.520 ‐ methods): "…95 patients participated in this double‐blind, parallel group trial."