Table 1.
Characteristics of cell lines used in this study
| Cell line | MP4131 | MP4631 | OCM-1A32 |
|---|---|---|---|
| Source | PDX of primary eye tumor | PDX of primary eye tumor | primary eye tumor |
| Oncogene mutation | GNA11(Q209L) | GNAQ(Q209L) | BRAF(V600E) |
| BAP1 status | wt | null | wt |
| Metastatic potential | low | high | - |
| FR responses: | |||
| Growth arrest16 | + | + | - |
| Reduced metabolism20 | + | + | - |
| Redifferentiation19 | + | - | - |
Reference table comparing the MP41, MP46, and OCM-1A cell lines. References for this information are cited as superscripts. Metastatic potential is based on clinical data from Gq/11-mutant UM tumor-only.