(A, B, C) H&E-stained sections of spleens from (A) male control, (B) male M-TTP KO, and (C) male M-triple KO mice at 9 wk of age (40X magnification). Red pulp was expanded by myeloid (M) and fewer erythroid (E) and megakaryocytic (Me) precursors in the M-triple KO spleens. (D, E, F) H&E-stained sections of lungs from (D) male control, (E) male M-TTP KO, and (F) male M-triple KO mice at 9 wk of age (20X magnification). Arrowheads indicate macrophages filling alveoli in lungs from M-TTP KO and M-triple KO mice. (G, H, I) H&E-stained sections of livers from (G) male control, (H) male M-TTP KO, and (I) male M-triple KO mice at 9 wk of age (20X magnification). Arrowheads indicate mononuclear cell infiltrates in livers from M-TTP KO and M-triple KO mice.