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. 2023 Nov;193(11):1789–1808. doi: 10.1016/j.ajpath.2023.02.019

Figure 4.

Figure 4

A–C: Fundus autofluorescence (A), optical coherence tomography (OCT) enface (B), and OCT cross-section (C) of a Western diet fed rhesus nonhuman primate 5 years after initiation of diet. A and B: Cotton-wool spots are clearly evident in the nasal region along the horizontal meridian adjacent to the optic disc. B and C: Green boxed area and green horizontal line (B) represent the level at which the OCT cross-section (C) was taken. OCT cross-section shows marked hyperreflectiveness (red arrowheads) in the nerve fiber layer.