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. 2023 Oct 17;13:1244341. doi: 10.3389/fonc.2023.1244341

Table 3.

Analyses of prognostic factors for survival.

Factor Overall survival Progression-free survival
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
HR(95%CI) P value HR(95%CI) P value HR(95%CI) P value HR(95%CI) P value
Treatment option
T+L+C/T+C/TACE 0.47(0.38-0.60) <0.001 0.49(0.39-0.62) <0.001 0.57(0.46-0.71) <0.001 0.59(0.48-0.73) <0.001
Age 0.99(0.97-1.01) 0.297 1.00(0.98-1.02) 0.751
Sex
Female/Male 0.79(0.48-1.29) 0.346 0.66(0.42-1.03) 0.069 0.80(0.50-1.27) 0.342
Etiology
Hepatitis B/Others 1.31(0.81-2.12) 0.273 1.21(0.78-1.87) 0.392
Cirrhosis
Yes/No 1.10(0.70-1.73) 0.687 1.22(0.80-1.86) 0.362
ECOG PS score
2/1 0.98(0.65-1.49) 0.929 1.08(0.73-1.58) 0.711
Child-Pugh class
B/A 1.26(0.65-2.44) 0.493 1.05(0.56-1.95) 0.889
ALBI grade
3/2/1 1.00(0.69-1.45) 0.983 0.97(0.69-1.37) 0.851
portal vein invasion
Yes/No 2.62(1.69-4.05) <0.001 2.54(1.63-3.94) <0.001 2.46(1.67-3.62) <0.001 2.46(1.67-3.62) <0.001
Extrahepatic metastasis
Yes/No 1.07(0.71-1.62) 0.754 1.10(0.76-1.62) 0.610
Number of tumors
3/2/1 1.04(0.84-1.27) 0.749 0.98(0.81-1.18) 0.803
Largest tumor size (cm)
≥10/<10 1.00(1.00-1.01) 0.425 1.00(1.00-1.01) 0.499
AFP level (μg/L)
≥400/<400 1.25(0.84-1.85) 0.278 1.11(0.78-1.60) 0.563

Analyses were performed using Cox proportional hazard regression model. HR, hazard ratio; CI, confidence interval; T+L+C, transarterial chemoembolization combined with lenvatinib plus camrelizumab; T+C, transarterial chemoembolization combined with camrelizumab; TACE, transarterial chemoembolization; ECOG-PS, Eastern Cooperative Oncology Group performance status; AFP, alpha-fetoprotein. HR and P values that are meaningful for multivariate analyses are in bold; bold is for eye-catching.