Table 4.
In subgroups defined by race/ethnicity and sex, association of selected upper airway measures with CASI score using a single multiple linear regression model for each subgroup
| Coefficient* | 95% CI | P-value | ||
|---|---|---|---|---|
| Black participants (N = 147) | ||||
| Soft palate volume (per sd) | 1.60 | 0.48 | 2.72 | 0.005 |
| Upper facial height (per sd) | 0.39 | -0.82 | 1.60 | 0.5 |
| Maxillary divergence (per sd) | 0.72 | -0.49 | 1.93 | 0.2 |
| Chinese-American participants (N = 88) | ||||
| Soft palate volume (per sd) | 0.68 | -0.69 | 2.04 | 0.3 |
| Upper facial height (per sd) | 0.10 | -1.42 | 1.63 | 0.9 |
| Maxillary divergence (per sd) | 1.67 | 0.17 | 3.18 | 0.03 |
| Hispanic participants (N = 108) | ||||
| Soft palate volume (per sd) | 0.62 | -1.24 | 2.48 | 0.5 |
| Upper facial height (per sd) | 0.11 | -1.61 | 1.84 | 0.9 |
| Maxillary divergence (per sd) | 0.89 | -0.66 | 2.44 | 0.3 |
| White participants (N = 228) | ||||
| Soft palate volume (per sd) | 0.07 | -0.76 | 0.89 | 0.9 |
| Upper facial height (per sd) | 1.43 | 0.63 | 2.23 | 0.001 |
| Maxillary divergence (per sd) | 0.41 | -0.46 | 1.28 | 0.4 |
| Female participants (N = 312) | ||||
| Soft palate volume (per sd) | 1.78 | 0.77 | 2.78 | 0.001 |
| Upper facial height (per sd) | 0.54 | -0.37 | 1.45 | 0.2 |
| Maxillary divergence (per sd) | 1.13 | 0.24 | 2.03 | 0.01 |
| Male participants (N = 259) | ||||
| Soft palate volume (per sd) | 0.18 | -0.49 | 0.85 | 0.6 |
| Upper facial height (per sd) | 0.83 | 0.10 | 1.56 | 0.03 |
| Maxillary divergence (per sd) | 0.39 | -0.38 | 1.16 | 0.3 |
*All models additionally adjusted for age, gender, site, current alcohol use, education, income, language spoken, and ApoE4 carrier status
CASI = Cognitive Abilities Screening Instrument