Supplementary Table 4.
Sensitivity analysis of associations between sitting time and kidney function decline-3 (n=132 123).
| Quartile 1 (n=32 947) | Quartile 2 (n=27 162) | Quartile 3 (n=37 810) | Quartile 4 (n=34 204) | P for trend | |
|---|---|---|---|---|---|
| Cases | 592 (1.8%) | 527 (1.9%) | 777 (2.1%) | 692 (2.0%) | 0.018 |
| Model 1 | 1 | 1.054 (0.937–1.185) | 1.101 (0.989–1.225) | 1.028 (0.921–1.147) | 0.486 |
| Model 2 | 1 | 1.065 (0.945–1.201) | 1.124 (1.008–1.253) | 1.151 (1.030–1.287) | 0.008 |
| Model 3 | 1 | 1.044 (0.923–1.182) | 1.106 (0.989–1.238) | 1.138 (1.015–1.277) | 0.016 |
The outcome was defined as an eGFR <60 mL/min/1.73 m2 and a rate of decline more than 1 mL/min/1.73 m2 per year, CKD-related hospitalization or death, or the presence of end-stage renal disease. Quartiles of sitting time: 1st quartile ≤17.4 h/week, 2nd quartile=17.5–27.9 h/week, 3rd quartile=28.0–36.9 h/week, 4th quartile ≥37 h/week. Model 1: Crude HR. Model 2: Adjusted for age, sex, current smoking, and current drinking. Model 3: Adjusted for covariates in Model 2 plus BMI, hypertension, diabetes, dyslipidaemia and MVPA. HR – hazard ratio; CI – confidence interval.