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. 2023 Nov;29(11):2403–2406. doi: 10.3201/eid2911.230987

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Timeline of events experienced by case-patient in Botswana from study of a rifampin-resistant TB variant not detectable using Xpert MTB/RIF assay (Cepheid, https://www.cepheid.com). Timeline events included routine laboratory procedures, study procedures, and timing of TB treatment. 2HRZ(E)/4HR, standard 6-month tuberculosis treatment regimen (2 months of isoniazid, rifampin and pyrazinamide, with or without ethambutol, followed by 4 months of isoniazid and rifampin); DST, drug susceptibility testing; EMB, ethambutol; INH, isoniazid; LFX, levofloxacin; MDR TB, multidrug-resistant tuberculosis; MFX, moxifloxacin; PZA, pyrazinamide; RMP, rifampin; SM, streptomycin; TB, tuberculosis; WGS, whole-genome sequencing; Xpert, GeneXpert.