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. 2023 Nov;29(11):2210–2217. doi: 10.3201/eid2911.231082

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Phylogenetic analysis of Neisseria meningitidis from different countries in study of detection of novel US N. meningitidis urethritis clade subtypes in Japan. Strains isolated from patients with IMD (red font) or STI (blue font), serogroup (NG or C), and country of origin are indicated. US_NmUC, J_NmUC, and J_NmUC-II N. meningitidis isolates have detailed profiles (Appendix 1 Table). We included 1 sequence type 11 N. meningitidis strain isolated in Japan from a patient with an STI (SK028) and 4 serogroup C meningococci (MenC) that were phylogenetically close to SK028 (PE5, PE6, PE7, and LNP26948) (29). Moreover, we included 7 MenC phylogenetically close to US_NmUC (IMD strains in the United States) (31), 2 sequence type 11 MenC isolated from IMD patients during 2003–2020 in Japan (NIID647 and NIID716) (28), and 6 MenC phylogenetically close to the 2 MenC from Japan (28). Scale bar indicates nucleotide substitutions per site. C, serogroup C; IMD, invasive meningococcal disease; NG, nongroupable; STI, sexually transmitted infection.