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. 2023 Sep 15;97(10):e01014-23. doi: 10.1128/jvi.01014-23

Fig 10.

Fig 10

Knockdown of hDSG2 and hCAR reduces SAdV GZ3-12 infection. (A) Knockdown of hDSG2 and hCAR significantly reduced SAdV GZ3-12 genomic DNA copy numbers post-infection in A549 cells. A549 cells pre-transfected with siRNAs were infected with SAdV GZ3-12 at 1 MOI. At 48 hpi, the viral genomic DNA in cells was quantified. Percent infection was calculated as the percentage of the viral genomic DNA copy number in cells transfected with siRNAs versus that in cells transfected with the scrambled control. (B) Knockdown of hCAR reduced HAdV-5 genomic DNA copy numbers post-infection in A549 cells. (C) Knockdown of hDSG2 reduced HAdV-55 genomic DNA copy numbers post-infection in A549 cells. (D) Knockdown of hCD46 reduced HAdV-3 genomic DNA copy numbers post-infection in A549 cells.