Table 2.

Developmental Domains Analyzed for Injury by Non-TORCH Pathogens or Infections

Developmental Domain	Defining Features	Example Clinical Diagnoses in the Child
Motor	Deficits in movement and coordination, typically diagnosed when difficulty with motor skills affects activities of daily living	Cerebral palsy
Intellectual/Cognitive	Permanent limitations of cognition and intelligence, characterized by deficits in learning, logical reasoning, problem-solving, interpersonal skills, practical skills defined by intelligence quotient of less than 70, or 2 standard deviations below the median.	Cognitive impairment
Learning	Impairments in academic function that are not due to sensory deficits, where difficulty is experienced with reading, writing, or mathematics	Dyslexia, dyscalculia, dysgraphia, nonverbal learning disorders
Communication	Speech Disorders: problems with articulation and fluency when speaking Language Disorders: difficulty comprehending and using spoken or written language (form, content, function)	Speech delay, language delay
Sensory	Disorders affecting somatosensory system (processing information related to vision, hearing, taste, smell and other special senses)	Sensorineural hearing loss, decreased visual acuity

This table shows the definitions of the developmental domains that were assessed for associations with maternal non-TORCH infections. For another developmental domain framework example with age-specific milestones, see [185].