Table 1.
Patient characteristics
| Parameter | N (%) |
|---|---|
| Sex | |
| Male | 181 (61.6) |
| Female | 113 (38.4) |
| Age, year | 62.0 (20.0; 83.0)* |
| Location | |
| Cecum | 7 (2.4) |
| Ascending | 57 (19.4) |
| Transverse | 14 (4.8) |
| Descending | 21 (7.1) |
| Rectum | 58 (19.7) |
| Rectosigmoid | 23 (7.8) |
| Sigmoid | 113 (38.4) |
| Synchronous | 1 (0.3) |
| Pathology | |
| Adenocarcinoma | 275 (93.5) |
| Mucinous | 17 (5.8) |
| Mucinous with signet ring carcinoma | 1 (0.3) |
| Signet ring cell carcinoma | 1 (0.3) |
| Differentiation | |
| Well differentiated | 5 (1.7) |
| Moderately differentiated | 249 (85.9) |
| Poorly differentiated | 36 (12.4) |
| N/A | 4 (1.4) |
| MSI status | |
| MSI-H | 16 (5.4) |
| MSI-L | 18 (6.1) |
| MSS | 258 (87.8) |
| N/A | 2 (0.7) |
| KRAS | |
| Mutant | 110 (37.4) |
| Wild type | 159 (54.1) |
| N/A | 25 (8.5) |
| BRAF | |
| Mutant | 4 (1.4) |
| Wild type | 42 (14.3) |
| N/A | 248 (84.4) |
| NRAS | |
| Mutant | 1 (0.3) |
| Wild type | 50 (17.0) |
| N/A | 243 (82.7) |
| Stage (AJCC) | |
| II | 65 (22.1) |
| III | 165 (56.1) |
| IV | 63 (21.4) |
| N/A | 1 (0.3) |
N, number of samples; MSI, microsatellite instability; MSS, microsatellite stability; MSI-H, high microsatellite instability; MSI-L, low microsatellite instability; N/A, not applicable; AJCC, American Joint Committee on Cancer.
*Median age of patients with CRC and overall range in this study.