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. 2023 Oct 19;21:5186–5200. doi: 10.1016/j.csbj.2023.10.038

Fig. 1.

Fig. 1

Introductory figure showing network-based drug repurposing. A) Mechanism of HPV infection leading to cervical cancer. B) Data collection for HPV-hosts, cervical cancer, and Human protein-protein interactions. C) Construction of shortest path source (HPV-host) to target (Cervical cancer) network (HPV2C). D) Obtaining key proteins and performing drug repurposing using network proximity analysis. E) Validation of the prediction.