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. 2023 Nov 1;4:37. doi: 10.1186/s43556-023-00147-x

Fig. 5.

Fig. 5

Overexpressing of SCARNA12 facilitated CRC cells growth via activating PI3K/AKT pathway. a KEGG pathway enrichment analysis of differentially expressed genes after SCARNA12 knockdown. b SCARNA12 activates the PI3K/AKT pathway. c Effect of AKT inhibitor MK2206 on p-AKT protein expression level in SW620 cells. d-e MK2206 reversed the SCARNA12-induced biological effects in SW620 cells. The results are presented as the mean ± SD (n ≥ 3). * P < 0.05, ** P < 0.01, *** P < 0.001